the effect of omega-3 supplementation on serum levels of brain derived neurotrophic factor (bdnf) and oxidative stress following plyometric training in active men

نویسندگان

محمد فاضل زاده

دانشجوی دکتری فیزیولوژی ورزشی، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه بیرجند، بیرجند، ایران ضیاء فلاح محمدی

دانشیار دانشگاه مازندران، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه مازندران، بابلسر، ایران

چکیده

the aim of this study was to investigate the effect of omega-3 supplementation with 4 weeks of plyometric training on serum changes of brain derived neurotrophic factor (bdnf) and oxidative stress and their relationship in active men. 28 physical education male students (age 23.21±1.98 year, height 174.25±5.34 cm, weight 66.83±7.49 kg, bmi 20.03±2.25 kg/m2) were randomly divided into four groups including training + omega-3, omega-3, training, control. the training and training+omega-3 (combination) groups performed selected plyometric training for 4 weeks in 2 or 3 sets with 6 to 12 repetitions. also, supplementary (omega-3) and combination groups daily consumed 2 gr. omega-3 and 1 gr. starch (as a capsule) 3 times per day after their meals. training group received placebo capsules (starch with similar weight combined by saffron to provide color for an appearance and taste similar to omega-3 capsules). anova was used to examine inter-group differences and pearson correlation coefficient was applied to investigate the existence of any relationships among variables. a significant increase was observed in bdnf serum levels in combined and supplementation groups compared with the control group (p=0.001, p=0.004 respectively). serum levels of mda decreased significantly in supplementation group compared with control group (p=0.002). also, serum levels of sod in training group increased significantly compared with control group (p=0.042). likewise, only a correlation observed was observed between mda and sod in supplementation group (p=0.048, r=0.759). regular consumption of omega-3 supplementation combined with plyometric training increases bdnf and reduces mda. consequently, it can be used as a beneficial method to increase the health of the nervous system and to resist oxidative stress induced by exercise training.

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عنوان ژورنال:
علوم زیستی ورزشی

جلد ۸، شماره ۳، صفحات ۲۹۵-۳۰۹

کلمات کلیدی
[ ' t h e a i m o f t h i s s t u d y w a s t o i n v e s t i g a t e t h e e f f e c t o f o m e g a ' , ' 3 s u p p l e m e n t a t i o n w i t h 4 w e e k s o f p l y o m e t r i c t r a i n i n g o n s e r u m c h a n g e s o f b r a i n d e r i v e d n e u r o t r o p h i c f a c t o r ( b d n f ) a n d o x i d a t i v e s t r e s s a n d t h e i r r e l a t i o n s h i p i n a c t i v e m e n . 2 8 p h y s i c a l e d u c a t i o n m a l e s t u d e n t s ( a g e 2 3 . 2 1 ± 1 . 9 8 y e a r ' , ' h e i g h t 1 7 4 . 2 5 ± 5 . 3 4 c m ' , ' w e i g h t 6 6 . 8 3 ± 7 . 4 9 k g ' , ' b m i 2 0 . 0 3 ± 2 . 2 5 k g / m 2 ) w e r e r a n d o m l y d i v i d e d i n t o f o u r g r o u p s i n c l u d i n g t r a i n i n g + o m e g a ' , 3 , ' o m e g a ' , 3 , ' t r a i n i n g ' , ' c o n t r o l . t h e t r a i n i n g a n d t r a i n i n g + o m e g a ' , ' 3 ( c o m b i n a t i o n ) g r o u p s p e r f o r m e d s e l e c t e d p l y o m e t r i c t r a i n i n g f o r 4 w e e k s i n 2 o r 3 s e t s w i t h 6 t o 1 2 r e p e t i t i o n s . a l s o ' , ' s u p p l e m e n t a r y ( o m e g a ' , ' 3 ) a n d c o m b i n a t i o n g r o u p s d a i l y c o n s u m e d 2 g r . o m e g a ' , ' 3 a n d 1 g r . s t a r c h ( a s a c a p s u l e ) 3 t i m e s p e r d a y a f t e r t h e i r m e a l s . t r a i n i n g g r o u p r e c e i v e d p l a c e b o c a p s u l e s ( s t a r c h w i t h s i m i l a r w e i g h t c o m b i n e d b y s a f f r o n t o p r o v i d e c o l o r f o r a n a p p e a r a n c e a n d t a s t e s i m i l a r t o o m e g a ' , ' 3 c a p s u l e s ) . a n o v a w a s u s e d t o e x a m i n e i n t e r ' , ' g r o u p d i f f e r e n c e s a n d p e a r s o n c o r r e l a t i o n c o e f f i c i e n t w a s a p p l i e d t o i n v e s t i g a t e t h e e x i s t e n c e o f a n y r e l a t i o n s h i p s a m o n g v a r i a b l e s . a s i g n i f i c a n t i n c r e a s e w a s o b s e r v e d i n b d n f s e r u m l e v e l s i n c o m b i n e d a n d s u p p l e m e n t a t i o n g r o u p s c o m p a r e d w i t h t h e c o n t r o l g r o u p ( p = 0 . 0 0 1 ' , ' p = 0 . 0 0 4 r e s p e c t i v e l y ) . s e r u m l e v e l s o f m d a d e c r e a s e d s i g n i f i c a n t l y i n s u p p l e m e n t a t i o n g r o u p c o m p a r e d w i t h c o n t r o l g r o u p ( p = 0 . 0 0 2 ) . a l s o ' , ' s e r u m l e v e l s o f s o d i n t r a i n i n g g r o u p i n c r e a s e d s i g n i f i c a n t l y c o m p a r e d w i t h c o n t r o l g r o u p ( p = 0 . 0 4 2 ) . l i k e w i s e ' , ' o n l y a c o r r e l a t i o n o b s e r v e d w a s o b s e r v e d b e t w e e n m d a a n d s o d i n s u p p l e m e n t a t i o n g r o u p ( p = 0 . 0 4 8 ' , ' r = 0 . 7 5 9 ) . r e g u l a r c o n s u m p t i o n o f o m e g a ' , ' 3 s u p p l e m e n t a t i o n c o m b i n e d w i t h p l y o m e t r i c t r a i n i n g i n c r e a s e s b d n f a n d r e d u c e s m d a . c o n s e q u e n t l y ' , ' i t c a n b e u s e d a s a b e n e f i c i a l m e t h o d t o i n c r e a s e t h e h e a l t h o f t h e n e r v o u s s y s t e m a n d t o r e s i s t o x i d a t i v e s t r e s s i n d u c e d b y e x e r c i s e t r a i n i n g . ' ]

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